バニリン

Product Name : バニリン

Physical State : Solid

Project number: P2016040701

Version No:1.0

Safety Data Sheet (Conforms to Regulation (EC) No 1907/2006 and Regulation (EC) No 2015/830)

Issue Date:11/04/2016

S.REACH.DEU.EN

SECTION 1 IDENTIFICATION OF THE SUBSTANCE / MIXTURE AND OF THE COMPANY / UNDERTAKING

 

1.1.Product Identifier

Product name   バニリン

Synonyms Chemical formula  C8H8O3

Other means of identification  Not Available

CAS number  121-33-5

EC number  204-465-2

1.2. Relevant identified uses of the substance or mixture and uses advised against

Relevant identified uses

used as fragrance in cosmetic and household products; used as food flavour

Uses advised against

Not Applicable

 

SECTION 2 HAZARDS IDENTIFICATION

2.1.Classification of the substance or mixture

Classification according to regulation (EC) No  1272/2008 [CLP]

Eye Irritation Category 2

2.2. Label elements Continued…

4-Hydroxy-3-methoxy-benzaldehydeNot Applicable

Not Applicable

CLP label elements SIGNAL WORD WARNING Hazard statement(s) H319

Causes serious eye irritation.

Supplementary statement(s)

Not Applicable

CLP classification (additional)

Not Applicable

Precautionary statement(s) Prevention

P280

Wear protective gloves/protective clothing/eye protection/face protection.

Precautionary statement(s) Response P305+P351+P338

IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

P337+P313

If eye irritation persists: Get medical advice/attention.

Precautionary statement(s) Storage

Precautionary statement(s) Disposal

2.3. Other hazards

REACh – Art.57-59: The mixture does not contain Substances of Very High Concern (SVHC) at the SDS print date.

SECTION 3 COMPOSITION / INFORMATION ON INGREDIENTS

3.1.Substances

1.CAS No

2.EC No

3.Index No

4.REACH No

%[weight]

Classification according to regulation (EC) No 1272/2008 [CLP]

1.121-33-5

2.204-465-2

3.Not Available

≥ 99.5

Eye Irritation Category 2; H319

3.2.Mixtures

See ‘Information on ingredients’ in section 3.1

SECTION 4 FIRST AID MEASURES

4.1. Description of first aid measures

General

If skin or hair contact occurs:

Flush skin and hair with running water (and soap if available).

Seek medical attention in event of irritation.

If this product comes in contact with the eyes:

Wash out immediately with fresh running water.

Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and moving the eyelids by occasionally lifting the upper and lower lids.

Seek medical attention without delay; if pain persists or recurs seek medical attention.

Removal of contact lenses after an eye injury should only be undertaken by skilled personnel.

If fumes, aerosols or combustion products are inhaled remove from contaminated area.

Other measures are usually unnecessary.

Immediately give a glass of water.

First aid is not generally required. If in doubt, contact a Poisons Information Centre or a doctor.

Eye Contact

If this product comes in contact with the eyes:

Wash out immediately with fresh running water.

Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and moving the eyelids by occasionally lifting the upper and lower lids.

Seek medical attention without delay; if pain persists or recurs seek medical attention.

Removal of contact lenses after an eye injury should only be undertaken by skilled personnel.

バニリン

Version No:1.0

Page 2 of 9

バニリン

Issue Date:11/04/2016

Continued…

ConfidentialSkin Contact

If skin or hair contact occurs:

Flush skin and hair with running water (and soap if available).

Seek medical attention in event of irritation.

Inhalation

If fumes, aerosols or combustion products are inhaled remove from contaminated area.

Other measures are usually unnecessary.

Ingestion

Immediately give a glass of water.

First aid is not generally required. If in doubt, contact a Poisons Information Centre or a doctor.

4.2 Most important symptoms and effects, both acute and delayed

See Section 11

4.3. Indication of any immediate medical attention and special treatment needed

Treat symptomatically.

SECTION 5 FIREFIGHTING MEASURES

5.1. Extinguishing media

There is no restriction on the type of extinguisher which may be used.

Use extinguishing media suitable for surrounding area.

5.2. Special hazards arising from the substrate or mixture

Fire Incompatibility

None known.

5.3. Advice for firefighters

Fire Fighting

Alert Fire Brigade and tell them location and nature of hazard.

Wear breathing apparatus plus protective gloves in the event of a fire.

Prevent, by any means available, spillage from entering drains or water courses.

Use fire fighting procedures suitable for surrounding area.

Fire/Explosion Hazard

Non combustible.

Not considered a significant fire risk, however containers may burn.

May emit corrosive fumes.

SECTION 6 ACCIDENTAL RELEASE MEASURES

6.1. Personal precautions, protective equipment and emergency procedures

See section 8

6.2. Environmental precautions

See section 12

6.3. Methods and material for containment and cleaning up

Minor Spills

Clean up all spills immediately.

Avoid breathing dust and contact with skin and eyes.

Wear protective clothing, gloves, safety glasses and dust respirator.

Use dry clean up procedures and avoid generating dust.

Major Spills

Moderate hazard.

CAUTION: Advise personnel in area.

Alert Emergency Services and tell them location and nature of hazard.

Control personal contact by wearing protective clothing.

6.4. Reference to other sections

Personal Protective Equipment advice is contained in Section 8 of the SDS.

SECTION 7 HANDLING AND STORAGE

7.1. Precautions for safe handling

Safe handling

Avoid all personal contact, including inhalation.

Wear protective clothing when risk of exposure occurs.

Use in a well-ventilated area.

Prevent concentration in hollows and sumps.

Fire and explosion

protection

See section 5

Other information

Store in original containers.

Keep containers securely sealed.

Store in a cool, dry area protected from environmental extremes.

Store away from incompatible materials and foodstuff containers.

7.2. Conditions for safe storage, including any incompatibilities

Suitable container

Polyethylene container.

Lined metal can, lined metal pail/ can.

Version No:1.0

Page 3 of 9

Issue Date:11/04/2016

Continued…

バニリンIngredient

Material name

TEEL-1

TEEL-2

TEEL-3

Ingredient

Original IDLH

Revised IDLH

Plastic pail.

Polyliner drum.

Storage incompatibility

None known

7.3. Specific end use(s)

See section 1.2

SECTION 8 EXPOSURE CONTROLS / PERSONAL PROTECTION

8.1. Control parameters

DERIVED NO EFFECT LEVEL (DNEL)

EXPOSURE PATTERN

WORKERS

GENERAL POPULATION

Short term – oral, systemic

effects

Not Available

10 mg/kg bw/day

Short term – inhalation,

local effects

10 mg/m³

Not Available

PREDICTED NO EFFECT LEVEL (PNEC)

COMPARTMENT

VALUE

Fresh Water

0.118 mg/L

Marine Water

0.0118 mg/L

Aqua

Not Available

Fresh water sediment

58.22 mg/kg sediment dw

Marine water sediment

5.822 mg/kg sediment dw

Soil

11.54 mg/kg soil dw

STP

10 mg/L

ORAL

Not Available

EMERGENCY LIMITS

バニリン

Vanilin

10 mg/m3

10 mg/m3

310 mg/m3

バニリン

Not Available

Not Available

8.2. Exposure controls

8.2.1. Appropriate

engineering controls

Engineering controls are used to remove a hazard or place a barrier between the worker and the hazard. Well-designed engineering controls can be highly

effective in protecting workers and will typically be independent of worker interactions to provide this high level of protection.

The basic types of engineering controls are:

Process controls which involve changing the way a job activity or process is done to reduce the risk.

Enclosure and/or isolation of emission source which keeps a selected hazard ‘physically’ away from the worker and ventilation that strategically ‘adds’ and

‘removes’ air in the work environment.

8.2.2. Personal protection

Eye and face protection

Safety glasses with side shields.

Chemical goggles.

Contact lenses may pose a special hazard; soft contact lenses may absorb and concentrate irritants. A written policy document, describing the wearing of

lenses or restrictions on use, should be created for each workplace or task.

Skin protection

See Hand protection below

Hands/feet protection

The selection of suitable gloves does not only depend on the material, but also on further marks of quality which vary from manufacturer to manufacturer. Where

the chemical is a preparation of several substances, the resistance of the glove material can not be calculated in advance and has therefore to be checked prior

to the application.

The exact break through time for substances has to be obtained from the manufacturer of the protective gloves and.has to be observed when making a final

choice.

Suitability and durability of glove type is dependent on usage.

Experience indicates that the following polymers are suitable as glove materials for protection against undissolved, dry solids, where abrasive particles are not

present.

polychloroprene.

nitrile rubber.

butyl rubber.

Body protection

See Other protection below

Version No:1.0

Page 4 of 9

Issue Date:11/04/2016

Continued…

バニリンOther protection

Overalls.

P.V.C. apron.

Barrier cream.

Thermal hazards

Not Available

Respiratory protection

Particulate. (AS/NZS 1716 & 1715, EN 143:000 & 149:001, ANSI Z88 or national equivalent)

8.2.3. Environmental exposure controls

See section 12

SECTION 9 PHYSICAL AND CHEMICAL PROPERTIES

9.1. Information on basic physical and chemical properties

Appearance

White or slightly yellow needle like crystal or crystalline powder

Physical state

Solid

Density

1,056 g/cm3 at 20°C

Odour

Partition coefficient

n-octanol / water

log Pow: 1,23 at 22°C

Odour threshold

Not Available

Auto-ignition temperature

(°C)

Not Available

pH (as supplied)

Not Available

Decomposition

temperature

Not Available

Melting point / freezing

point (°C)

81 – 83

Viscosity (cSt)

Not Available

Initial boiling point and

boiling range (°C)

170 °C at 20 hPa

Molecular weight (g/mol)

Not Available

Flash point (°C)

153 °C – closed cup

Taste

Not Available

Evaporation rate

Not Available

Explosive properties

Not Available

Flammability

Not flammable

Oxidising properties

Not Available

Upper Explosive Limit (%)

Not Available

Surface Tension (dyn/cm or

mN/m)

Not Applicable

Lower Explosive Limit (%)

Not Available

Volatile Component (%vol)

Not Available

Vapour pressure (kPa)

1 hPa at 107 °C；< 0,01 hPa at 25 °C

Gas group

Not Available

Solubility in water (g/L)

10 g/l at 25°C

pH as a solution (1%)

Not Available

Vapour density (Air = 1)

Not Available

VOC g/L

Not Available

9.2. Other information

Not Available

SECTION 10 STABILITY AND REACTIVITY

10.1.Reactivity

See section 7.2

10.2.Chemical stability

Product is considered stable and hazardous polymerisation will not occur.

10.3. Possibility of

hazardous reactions

See section 7.2

10.4. Conditions to avoid

See section 7.2

10.5. Incompatible materials

See section 7.2

10.6. Hazardous

decomposition products

See section 5.3

SECTION 11 TOXICOLOGICAL INFORMATION

11.1. Information on toxicological effects

Inhaled

The material is not thought to produce adverse health effects or irritation of the respiratory tract (as classified by EC Directives using animal models).

Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable control measures be used in an occupational setting.

Ingestion

The material has NOT been classified by EC Directives or other classification systems as ‘harmful by ingestion’. This is because of the lack of corroborating

animal or human evidence.

Skin Contact

The material is not thought to produce adverse health effects or skin irritation following contact (as classified by EC Directives using animal models).

Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable gloves be used in an occupational setting.

Eye

This material can cause eye irritation and damage in some persons.

Chronic

Long-term exposure to the product is not thought to produce chronic effects adverse to the health (as classified by EC Directives using animal models);

nevertheless exposure by all routes should be minimised as a matter of course.

バニリン

TOXICITY

IRRITATION

Version No:1.0

Page 5 of 9

Issue Date:11/04/2016

Continued…

Sweet,milk fragrance and vanilla aroma

バニリンIngredient

Persistence: Water/Soil

Persistence: Air

Ingredient

Bioaccumulation

Ingredient

Mobility PBT

Relevant available data

Not Available

Not Available

Not Available

PBT Criteria fulfilled?

Not Available

Not Available

Not Available

Intraperitoneal (mouse) LD50: 475 mg/kg[2]

Nil reported

Intraperitoneal (rat) LD50: 1160 mg/kg[2]

Oral (guinea pig) LD50: 1400 mg/kg[2]

Oral (Mouse) LD50: 1480 mg/kg[2]

Oral (rat) LD50: 1580 mg/kg[2]

Subcutaneous (Rat) LD50: 1500 mg/kg[2]

Legend:

1. Value obtained from Europe ECHA Registered Substances – Acute toxicity 2.* Value obtained from manufacturer’s SDS. Unless otherwise specified data

extracted from RTECS – Register of Toxic Effect of chemical Substances

バニリン

For certain benzyl derivatives:

The members of this group are rapidly absorbed through the gastrointestinal tract, metabolised primarily in the liver, and excreted primarily in the urine either

unchanged or as conjugates of benzoic acid derivatives. At high dose levels, gut micro-organisms may act to produce minor amounts of breakdown products.

However, no adverse effects have been reported even at repeated high doses. Similarly, no effects were observed on reproduction, foetal development and

tumour potential.

Forvanillin:

Vanillingenerally does not cause irritation or sensitisation of the skin but sometimesdoes cause inflammation. It causes positive reactions to people already

sensitisedto Balsam of Peru, and is considered a secondary allergen. It is not consideredto cause reproductive toxicity or toxic effects to the embryo. Vanillin

doesnot cause birth defects.

Miosis, somnolence, muscle weakness, coma, respiratory stimulation, maternal effects involving ovaries, fallopian tubes, uterus, cervix and vagina recorded.

Legend:

– Data available but does not fill the criteria for classification

– Data required to make classification available

– Data Not Available to make classification